Fentanyl, administered in the Duragesic Patch, is a powerful narcotic
painkiller for serious pain. It is generally only prescribed for long-lasting
relief from intense, persistent and chronic pain. The Duragesic patch
should only be used when less potent medicines have proved ineffective
and pain needs to be controlled 24/7.
Duragesic patches are a transdermal system providing 72 hours of
continuous systemic delivery of this potent opioid analgesic.
Duragesic is available in 4 color-coded patch strengths: 25 mg, 50
mg, 75 mg, and 100 mcg/hour. As with all pure opioid agonists, there
is no analgesic ceiling effect with fentanyl, thus there are no dose-limiting
adverse effects, and dosages can be gradually increased until adequate
pain relief is achieved.
Duragesic should never be used in the following situations:
- where the right dosage hasn't been established in
advance – for instance, after an operation or
- for mild or intermittent pain that responds to other
- in children under 12 or teenagers who weigh less
than 110 pounds.
What are the side effects of Duragesic?
Typical side effects of Duragesic therapy include abdominal pain,
anxiety, confusion, constipation, depression, diarrhea, dizziness,
dry mouth, euphoria, hallucinations, headache, impaired or interrupted
breathing, indigestion, itching, anorexia, nausea, agitation, shortness
of breath, sleepiness, sweating, urinary retention, vomiting, and
What are the symptoms of Duragesic overdose
Users are susceptible to an overdose if they take too much transdermal
fentanyl, or combine it with excessive amounts of another narcotic.
An overdose can cause severe breathing problems (breathing may even
stop), unconsciousness, and death. Serious signs of an overdose include
very slow breathing and drowsiness so severe the person is unresponsive.
Other signs of an overdose include cold, clammy skin; low blood pressure;
pinpoint pupils of eyes; and slow heartbeat. If this occurs, get emergency
help right away